| 发明名称 | Use of CI-994 and dinaline for the treatment of memory/cognition and anxiety disorders | ||
| 摘要 | The invention relates to methods and compositions for promoting cognitive function and/or treating cognitive function disorders and impairments. In particular the methods are accomplished by administering to a subject CI-994 or dinaline or a pharmaceutically acceptable salt, ester, prodrug or metabolite thereof. | ||
| 申请公布号 | US8841346(B2) | 申请公布日期 | 2014.09.23 |
| 申请号 | US201213595048 | 申请日期 | 2012.08.27 |
| 申请人 | Massachusetts Institute of Technology;The Broad Institute, Inc.;The General Hospital Corporation | 发明人 | Tsai Li-Huei;Guan Ji-Song;Haggarty Stephen J.;Holson Edward;Wagner Florence;Graeff Johannes |
| 分类号 | A01N37/18;A61K31/16;A61K31/165;A61K31/195;C07C237/42;A61K45/06;A61K31/167 | 主分类号 | A01N37/18 |
| 代理机构 | Wolf, Greenfield & Sacks, P.C. | 代理人 | Wolf, Greenfield & Sacks, P.C. |
| 主权项 | 1. A method of treating cognitive function or impairments in a subject in need thereof comprising: systemically administering to the subject an effective amount of 4-(acetylamino)-N-(2aminophenyl)benzamide (CI-994) or dinaline or a pharmaceutically acceptable salt. | ||
| 地址 | Cambridge MA US | ||