Methods of reducing aggregation of a protein or proteins in a formulation, and protein formulations having reduced aggregation properties are provided. The methods and formulations described herein maintain the biological activity of a protein and increase the shelf life of protein formulations.
申请公布号
CA2646934(C)
申请公布日期
2014.09.23
申请号
CA20072646934
申请日期
2007.03.19
申请人
WYETH
发明人
WARNE, NICHOLAS, WILLIAM;KANTOR, ANGELA;CROWLEY, THOMAS JOSEPH;SOLEY, ERIN, CHRISTINE;LI, LI;LUKSHA, NICHOLAS GARY;NEIDHARDT, EDIE ANNA