发明名称 NOVEL OCTAHYDROQUINOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND THEIR APPLICATIONS
摘要 PROBLEM TO BE SOLVED: To provide novel compounds having dopamine Dreceptor agonist action.SOLUTION: The invention provides octahydroquinoline derivatives represented by the specified general formula (I) or pharmacologically acceptable salts thereof. In the formula, Ris Calkyl or the like, Ris hydrogen or Calkyl, Rand Rare each hydrogen, Calkyl, substituted or unsubstituted heteroaryl Calkyl, RRN-Calkyl, or the like. The compounds have excellent dopamine Dreceptor stimulation action, and thereby are useful as therapeutic or preventive agents for Parkinson disease or the like.
申请公布号 JP2014172873(A) 申请公布日期 2014.09.22
申请号 JP20130047624 申请日期 2013.03.11
申请人 KISSEI PHARMACEUTICAL CO LTD 发明人 NISHIMURA TOSHIHIRO ; UENO YASUNORI ; KASAI KIYOSHI ; YOSHIDA MASAKO ; TERANISHI HIROTAKA
分类号 C07D471/04;A61K31/4365;A61K31/437;A61K31/4375;A61K31/444;A61K31/4545;A61K45/00;A61P5/08;A61P25/16;A61P43/00;C07D495/04;C07D513/04 主分类号 C07D471/04
代理机构 代理人
主权项
地址
您可能感兴趣的专利