CRYSTAL HAVING CRYSTAL HABIT AND PHARMACEUTICAL COMPOSITION CONTAINING THE CRYSTAL AS ACTIVE COMPONENT

摘要

PROBLEM TO BE SOLVED: To provide means for improving solubility of luliconazole.SOLUTION: There is provided a crystal of luliconazole having such a crystal habit that a (011) plane is a specific crystal growth plane. In diffraction peaks detected in the range of 2θ=5° to 2θ=35°of the powder X-ray diffraction pattern using a radiation of CuKα-line as a radiation source, the crystal has 25% or more of Ito a total sum of I, I, I, I, Iand the like, in which integrated intensities of the diffraction peaks which correspond to the (001), (100), (10-1), (011), and (110) planes are designated as I, I, I, I, and Irespectively.