| 摘要 |
PROBLEM TO BE SOLVED: To prevent, in one embodiment, a hard capsule formulation including a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, from deteriorating due to gastric fluid that penetrates into the hard capsule shell.SOLUTION: A hard capsule formulation comprises a hard capsule with acid resistance; the hard capsule is not treated with an enteric coating; and the hard capsule formulation is characterized by comprising an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule. |
