MULTIPLE IMPACT MICROPROJECTION APPLICATORS AND METHODS OF USE

摘要

Applicators for a microprojection array capable of multiple impacts and methods of using the applicators are described.

主权项

1. A method of delivering a therapeutic agent to a subject, comprising:
applying to a skin site of a subject, an applicator comprising at least one plunger element, at least one microprojection retained on a distal surface of the plunger, and an actuator; actuating the actuator to convey an external force to the at least one plunger element such that an energy required for the at least one microprojection to penetrate the skin site is delivered in multiple, discrete quanta and/or impacts.