发明名称 Process for synthesizing GGA and its derivatives
摘要 This invention relates to processes for synthesizing GGA or GGA derivatives and intermediates involved therein.
申请公布号 US2014275631(A1) 申请公布日期 2014.09.18
申请号 US201313815805 申请日期 2013.03.15
申请人 COYOTE PHARMACEUTICALS, INC. 发明人 Abril-Horpel Obsidiana;Haag William;Pierson Ann
分类号 C07C45/42;C07C45/29 主分类号 C07C45/42
代理机构 代理人
主权项 1. A process for preparing a compound of formula (I): said process comprising: hydrolyzing a compound of formula (II): wherein: X and Y are each independently OR6, SR6, or X and Y together with the carbon atom they are attached to form a ring of formula: wherein each R6 is independently C1-C6 alkyl, each X1 and X2 are independently O, or S; q is 1 or 2; each X3 is independently C1-C6 alkyl; t is 0, 1, 2, or 3, and each of R1, R2, R3, R4, and R5 is independently H or C1-C6 alkyl or R1 and R2 together with the carbon atom they are joined to form a C5-C6 cycloalkyl optionally substituted with 1-3 C1-C6 alkyl.
地址 MENLO PARK CA US