PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL RHAMNOSE CARBAMATES

摘要

Aryl boronic esters containing the rhamnose carbamate moiety are prepared in good yield and without cleavage of the carbamate linkage by first contacting p-bromophenyl isocyanate with a tetrahydropyran-2-ol followed by reaction with a diboron compound.

主权项

1. A compound of formula (III) wherein R, R1 and R2 independently represent C1-C4 alkyl, C3-C4 alkenyl or C1-C4 fluoroalkyl, and R3 and R4 independently represent H, C1-C4 alkyl, or when taken together form an ethylene or propylene group optionally substituted with from one to four CH3 groups.