BACTERIA AND METHOD FOR SYNTHESIZING FATTY ACIDS

摘要

The present invention discloses a process for increasing the production of free fatty acids at high yield (close to maximum theoretical yield), with various fatty acid compositions and various percentage of fatty acids accumulated intracellularly. This invention will enable the efficient production of other products derived from free fatty acids and/or products that can be branched out from the fatty acid synthesis pathways.

主权项

1. A genetically engineered bacteria for producing fatty acids, said bacteria comprising a genotype comprising:
b) an overexpressed acyl ACP thioesterase (TE+); c) one or more of an overexpressed FabZ+, FadR+, or FabH+; d) zero, one or more of a ΔfadR, ΔsucC, ΔfabR, ΔfadD, or ΔptsG; with the proviso that said bacteria does not have a genotype of ΔfadD ΔsucC TE+.