COMPOSITIONS AND ASSOCIATED METHODS FOR RADIOISOTOPE-BINDING MICROPARTICLES

摘要

The present disclosure relates to polymeric materials that may be labeled with a radioisotope, to processes for producing the labeled polymeric material, and to methods of using the materials in analytical and therapeutic applications. Specifically, the disclosure relates to injectable and implantable microparticles, such as microspheres, which are associated with radioisotopes such that the microparticles are both therapeutic and detectable. The radioisotope-containing microparticles are useful for embolization and other therapeutic medical applications.

主权项

1. A microparticle, comprising a polymer having a diameter ranging from about 1 micrometer to about 2000 micrometer, the polymer comprising at least one type of polymerized monomer and a chelating agent, the chelating agent configured to chelate a radioisotope.