| 摘要 |
<p>The present invention relates to methods for managing the risk for pathologies and employing either absolute levels of, or changes over time, for the generation of individual- specific dietary guidance. The method comprises comparing one or more biomarker(s) against thresholds. This comparison provides a score for the individual's risk of developing a pathology, such as type-2 diabetes or weight gain. The biomarkers may be fatty acids, generally, and palmitoleic acid (POA) and/or di-homo gamma-linolenic acid (DGLA) in particular. Samples are collected from the individual and are used to analyze the levels of the biomarkers. The samples can be whole blood, serum, plasma, and buccal mucosa cells, for example. High or increasing levels of the biomarkers indicate that carbohydrate intake is above the individual's metabolic tolerance.</p> |
