| 发明名称 |
AMIDOMETHYL-SUBSTITUTED OXINDOLE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF VASOPRESSIN-DEPENDENT ILLNESSES |
| 摘要 |
The present invention relates to novel amidomethyl-substituted oxindole derivatives, pharmaceutical compositions comprising them, and their use for the treatment of vasopressin-dependent disorders. |
| 申请公布号 |
US2014275110(A1) |
申请公布日期 |
2014.09.18 |
| 申请号 |
US201414251384 |
申请日期 |
2014.04.11 |
| 申请人 |
AbbVie Deutschland GmbH & Co. KG |
发明人 |
Oost Thorsten;Netz Astrid;Geneste Hervé;Braje Wilfried;Wernet Wolfgang;Unger Liliane;Hornberger Wilfried;Lubisch Wilfried |
| 分类号 |
C07D401/14 |
主分类号 |
C07D401/14 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A compound of the formula I in which R1 is hydrogen, methoxy or ethoxy; R2 is hydrogen or methoxy; R3 is hydrogen, methyl, ethyl, n-propyl or isopropyl; X1 and X2 are N or CH, with the proviso that X1 and X2 are not simultaneously N; and their pharmaceutically acceptable salts and prodrugs thereof. |
| 地址 |
Wiesbaden DE |
