发明名称 |
Bioerodible Silicon-Based Compositions for Delivery of Therapeutic Agents |
摘要 |
The invention comprises a composition comprising a bioerodible porous silicon-based carrier material wherein the carrier material carries at least one large molecule therapeutic agent and at least one amorphous sugar, optionally further comprising a crystallization inhibitor. The composition may be used in vitro or in vivo to deliver the therapeutic agent, preferably in a controlled fashion over an intended period of time such as over multiple days, weeks or months. The composition may be used for treating or preventing conditions of a patient such as chronic diseases. |
申请公布号 |
US2014271886(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
US201414211170 |
申请日期 |
2014.03.14 |
申请人 |
pSivida Corp |
发明人 |
Barnett Christian;Ashton Paul;Canham Leigh T. |
分类号 |
A61K9/14;A61K38/42;C07K16/22 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
1. A composition comprising a bioerodible porous silicon-based carrier material wherein the carrier material comprises at least one large molecule therapeutic agent and an amorphous sugar. |
地址 |
Watertown MA US |