发明名称 |
SPRAY-DRIED POWDER COMPRISING VANCOMYCIN HYDROCHLORIDE, AND INDUSTRIAL MANUFACTURING METHOD THEREOF |
摘要 |
The present invention provides a spray-dried powder comprising vancomycin hydrochloride, and an industrial manufacturing method thereof. The industrial manufacturing method comprises: using a vancomycin hydrochloride solution with the purity of not lower than 95%, adding a stabilizing agent and a solubilizing agent in the solution to increase the stability and the concentration of the solution, concentrating the vancomycin hydrochloride composite solution to 20%-30wt.%, and performing spray drying in this concentration to obtain a vancomycin hydrochloride spray-dried powder with the impurity B of lower than 1.5%. |
申请公布号 |
WO2014139329(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
WO2014CN00268 |
申请日期 |
2014.03.14 |
申请人 |
SUN, XINQIANG;ZHAO, JUNXING |
发明人 |
SUN, XINQIANG;ZHAO, JUNXING |
分类号 |
A61K9/14;A61K38/14;A61P31/04;C12N1/20 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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