发明名称 |
GUANIDINOBENZOIC ACID ESTER COMPOUND |
摘要 |
[Problem] To provide a compound useful as a drug for preventing and/or treating kidney disease. [Solution] The inventors studied compounds having trypsin-inhibiting activity, confirmed that guanidinobenzoic acid ester compounds have trypsin-inhibiting activity, and completed the invention. These guanidinobenzoic acid ester compounds can be used as drugs for the prevention and/or treatment of kidney disease (for example, chronic kidney disease, acute glomerulonephritis, acute renal failure, and the like) as alternative drugs to a low-protein diet, and/or as drugs for the prevention and/or treatment of diseases in which trypsin participates (for example, chronic pancreatitis, reflux esophagitis, hepatic encephalopathy, influenza, and the like). |
申请公布号 |
CA2905606(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
CA20142905606 |
申请日期 |
2014.03.13 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
FUJIYASU, JIRO;ASANO, TORU;YAMAKI, SUSUMU;KANEKO, OSAMU;KOIKE, YUKA;IMAIZUMI, TOMOYOSHI;URANO, YASUHARU;SATOU, TOMOHKI;SASAMURA, SATOSHI |
分类号 |
C07C279/18;A61K31/24;A61K31/343;A61K31/381;A61K31/472;A61P13/12;C07D217/26;C07D307/80;C07D333/40;C07D333/68;C07D333/70 |
主分类号 |
C07C279/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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