发明名称 GUANIDINOBENZOIC ACID ESTER COMPOUND
摘要 [Problem] To provide a compound useful as a drug for preventing and/or treating kidney disease. [Solution] The inventors studied compounds having trypsin-inhibiting activity, confirmed that guanidinobenzoic acid ester compounds have trypsin-inhibiting activity, and completed the invention. These guanidinobenzoic acid ester compounds can be used as drugs for the prevention and/or treatment of kidney disease (for example, chronic kidney disease, acute glomerulonephritis, acute renal failure, and the like) as alternative drugs to a low-protein diet, and/or as drugs for the prevention and/or treatment of diseases in which trypsin participates (for example, chronic pancreatitis, reflux esophagitis, hepatic encephalopathy, influenza, and the like).
申请公布号 CA2905606(A1) 申请公布日期 2014.09.18
申请号 CA20142905606 申请日期 2014.03.13
申请人 ASTELLAS PHARMA INC. 发明人 FUJIYASU, JIRO;ASANO, TORU;YAMAKI, SUSUMU;KANEKO, OSAMU;KOIKE, YUKA;IMAIZUMI, TOMOYOSHI;URANO, YASUHARU;SATOU, TOMOHKI;SASAMURA, SATOSHI
分类号 C07C279/18;A61K31/24;A61K31/343;A61K31/381;A61K31/472;A61P13/12;C07D217/26;C07D307/80;C07D333/40;C07D333/68;C07D333/70 主分类号 C07C279/18
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