发明名称 COMPOSITION FOR ORAL ADMINISTRATION FOR BINDING ALDEHYDES IN THE GASTROINTESTINAL TRACT
摘要 The present invention relates to a non-toxic composition containing one or more cysteine compounds selected from L- or D-cysteine, N-acetyl cysteine, and the pharmaceutically acceptable salts thereof, for decreasing the risk of a subject contracting cancer of the stomach, the small intestine and the colon, by locally binding aldehydes present in the stomach, and optionally also separately the aldehydes carried to the small intestine or the colon, or both, whereby the composition is formulated with the help of two or more additives into controlled-release tablets containing at least one additive selected from cationic and gel- forming polymers, which tablets are formed from two or more separate layers with different release profiles, whereby the cysteine compounds are added both into the inner layer(s) and into the tablet material surrounding these.
申请公布号 CA2905236(A1) 申请公布日期 2014.09.18
申请号 CA20132905236 申请日期 2013.03.12
申请人 BIOHIT OYJ 发明人 SUOVANIEMI, OSMO
分类号 A61K31/198;A61K9/16;A61P1/04 主分类号 A61K31/198
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