发明名称 PEPTIDE SYSTEMS AND METHODS FOR METABOLIC CONDITIONS
摘要 The present invention generally relates to compositions and methods for topical or transdermal delivery, and treatment of metabolic conditions. In some cases, the composition may include nitric oxide and/or peptides such as thyrotropin-releasing hormone (TRH) and/or GnRH (gonadotropin-releasing hormone). The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other structures containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.
申请公布号 US2014271934(A1) 申请公布日期 2014.09.18
申请号 US201314096065 申请日期 2013.12.04
申请人 Transdermal Biotechnology, Inc. 发明人 Perricone Nicholas V.
分类号 A61K38/22;A61K38/28;A61K33/00 主分类号 A61K38/22
代理机构 代理人
主权项 1. A method, comprising: administering, to the skin of a subject having a metabolic condition, a composition comprising an effective amount of gonadotropin-releasing hormone (GnRH) and nitric oxide to treat the metabolic condition, and a carrier having a phosphatidylcholine component entrapping the nitric oxide.
地址 Meriden CT US