发明名称 |
METHOD OF GENERATING AN INDEX SCORE FOR MBL DEFICIENCY TO PREDICT CARDIODIABETES RISK |
摘要 |
<p>This application relates to methods of predicting susceptibility or likelihood of a clinically-relevant mannose-binding lectin (MBL)-deficient subject to develop a cardiovascular disease and/or cardiodiabetes. The methods include measuring MBL mass or concentration and, optionally, measuring MBL activity, at least one other biomarker and/or or genotyping of MBL gene and its promoters; combining the information obtained into a calculated MBL- inclusive index score that involves mathematical transformation; and assigning a risk of cardiadiabetic status and clinical endpoints based on the determination and comparison of the MBL inclusive index to reference values from a population.</p> |
申请公布号 |
WO2014145836(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
WO2014US30668 |
申请日期 |
2014.03.17 |
申请人 |
HEALTH DIAGNOSTIC LABORATORY, INC. |
发明人 |
CAFFREY, REBECCA, E.;POTTALA, JAMES;VARVEL, STEPHEN |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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