| 摘要 |
A system, method and computer program product to determine radiation dose from radionuclides used to treat a patient in need thereof. The present invention allows users to visualize and understand the impact of radionuclide choice, distribution of activity in the cell, distribution of activity among the cells, cell dimensions, cell separation distance, cluster size, and radiobiological response parameters on the capacity to kill populations of cells. All of these parameters can play a substantial role in determining the surviving fraction of cells. Accordingly, this system, method and computer program product can assist in designing treatment plans for therapeutic radiopharmaceuticals suited to individual needs. |
| 主权项 |
1. A computing-implemented method of determining a dose of radiation for a patient for radiation therapy treatment planning, the method comprising:
receiving, by a computing device, one or more features associated with a dose of radiation; displaying, by the computing device, a menu of one or more of the features associated with the dose of radiation, wherein each feature corresponds to a category of information; receiving, by the computing device from the user, a selection of one or more feature from the menu of features; and for each selected feature:
receiving, by the computing device, information pertaining to the selected feature,determining, by the computing device radiation data for a radionuclide,determining, by the computing device a radiobiological parameter,determining, by the computing device a target volume and source volume,determining, by the computing device a cell geometry, anddetermining, by the computing device, a dose of radiation based upon the selected features. |
