Chelation Suppository for Improved Drug Delivery

摘要

Described herein is a method of delivering drugs to the blood stream directly by absorption through cell membranes in the wall of the rectum from a rectal suppository comprising a glyceride based excipient More specifically, CaNa2 EDTA is delivered rectally from a suppository containing water soluble, glyceride based excipient/carrier.

主权项

1. A suppository for use in chelating heavy metals in a living being comprising:
i. calcium disodium ethylenediaminetetraacetate (CaNa2 EDTA), ii. one or more hydrophobic excipients, and iii. a carrier comprising one or more of glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids, cocoa butter, and fatty acids.