发明名称 SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES
摘要 Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel semicarbazides, sulfonyl carbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to Arenaviridae (Junin, Machupo, Guanavito, Sabia and Lassa), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).;
申请公布号 US2014275037(A1) 申请公布日期 2014.09.18
申请号 US201314134165 申请日期 2013.12.19
申请人 Siga Technologies, Inc. 发明人 Deng Yijun;Nitz Theodore J.;Bailey Thomas R.;Zhang Yanming;Laquerre Sylvie
分类号 C07C311/49;C07D285/06;C07D231/18;C07D295/26;C07D213/74;C07D317/48;C07D277/36;C07D261/10;C07D233/84;C07D295/195;C07C275/40;C07D265/36;C07D319/18 主分类号 C07C311/49
代理机构 代理人
主权项
地址 Corvallis OR US