发明名称 |
TREATMENT FOR DIABETES IN PATIENTS INAPPROPRIATE FOR METFORMIN THERAPY |
摘要 |
The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for treating and/or preventing metabolic diseases, particularly diabetes, in patients for whom metformin therapy is inappropriate due to intolerability or contraindication against metformin. |
申请公布号 |
US2014274890(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
US201414294630 |
申请日期 |
2014.06.03 |
申请人 |
DUGI Klaus;GRAEFE-MODY Eva Ulrike;HARPER Ruth;WOERLE Hans-Juergen |
发明人 |
DUGI Klaus;GRAEFE-MODY Eva Ulrike;HARPER Ruth;WOERLE Hans-Juergen |
分类号 |
A61K31/522;A61K45/06 |
主分类号 |
A61K31/522 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating and/or preventing type 2 diabetes mellitus in a patient for whom metformin therapy is inappropriate due to intolerability or contraindication against metformin comprising orally administering to the patient a DPP-4 inhibitor, which is 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(R)-amino-piperidin-1-yl)-xanthine or a pharmaceutically acceptable salt thereof, wherein said DPP-4 inhibitor is administered in an oral dose of 5 mg per day to said patient. |
地址 |
Dresden DE |