发明名称 |
DESETHYLHYDROXYCHLOROQUINE FOR THE TREATMENT OF DISEASES ASSOCIATED WITH INFLAMMATION |
摘要 |
Compositions and methods are provided for inhibiting or treating the early and established stages of inflammatory diseases by administration of an effective dose of the desethylhydroxychloroquine (DHCQ). A benefit of the methods is the ability to deliver a dose of agent that is effective in treating inflammation while sparing the individual from retinal toxicity. |
申请公布号 |
US2014275164(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
US201414214307 |
申请日期 |
2014.03.14 |
申请人 |
The United States Government As Represented By The Department of Veterans Affairs ;The Board of Trustees of the Leland Stanford Junior University |
发明人 |
Robinson William H.;Sokolove Jeremy;Wang Qian |
分类号 |
A61K31/4706;A61K31/40 |
主分类号 |
A61K31/4706 |
代理机构 |
|
代理人 |
|
主权项 |
1. A pharmaceutical composition comprising:
a dose of an aminoquinoline or salt and/or ester thereof effective in treating inflammation with decreased retinal toxicity; and a pharmaceutically acceptable excipient. |
地址 |
Washington DC US |