Small molecule inhibitors of Nrf2 and methods of their use are provided for treating or preventing a disease, disorder or condition associated with an Nrf2- regulated pathway. The compound can be administered as a single agent or can be administered to enhance the efficacy of a chemotherapeutic drug and/or radiation therapy.
申请公布号
WO2014145642(A2)
申请公布日期
2014.09.18
申请号
WO2014US30442
申请日期
2014.03.17
申请人
THE JOHNS HOPKINS UNIVERSITY;THE NATIONAL INSTITUTES OF HEALTH