发明名称 MATRIX METALLOPROTEASE (MMP) TARGETED AGENTS FOR IMAGING AND THERAPY
摘要 The present invention provides compound conjugates of matrix metalloprotease inhibitors and linked metal chelators which are useful for imaging solid tumors and treating and diagnosing certain types of diseases such as cancer.
申请公布号 US2014271465(A1) 申请公布日期 2014.09.18
申请号 US201414208350 申请日期 2014.03.13
申请人 Mallinckrodt LLC 发明人 Freskos John N.;Dyszlewski Mary;Chinen Lori;Knight Hector;Schmidt Michelle
分类号 A61K51/04;A61K45/06;A61K31/4545;C07D211/66;C07D401/12;A61K31/4523 主分类号 A61K51/04
代理机构 代理人
主权项 1. A compound conjugate comprising a matrix metalloprotease inhibitor (MMPi) portion and a linked metal chelator portion.
地址 Hazelwood MO US