A TUBE WITH MODIFIED INNER WALL SURFACE AND PREPARATION METHOD THEREOF

摘要

The present invention relates to a method for preparing a tube, comprising a step for modifying the inner wall surface of a tube using plasma. Provided are a method for preparing the tube comprises a step for preparing a tube; a step for modifying the inner wall surface of the tube using plasma to have reactivity, a step for forming a thin film layer for prevention of aging or adhesion on the modified inner wall surface, and a step for modifying the surface of the thin film using microplasma to improve the cell adhesive property; and a polymer tube for transplantation prepared by the method. The present invention processes the inner wall surface of a polymer tube by sequentially: 1) modifying the inner wall surface with microplasma to have reactivity; 2) introducing a hydrocarbon thin film; and 3) additionally modifying the inner wall surface with microplasma to improve the cell adhesive property, so that the adhesive property of smooth muscle cells to the modified inner wall surface is improved and thereby the polymer tube can be used as an artificial vessel transplantable in the body. Particularly, the present invention can evenly modify the inner wall surface of a tube having a narrow internal diameter of millimeters by employing the preparing method using microplasma treatment.