| 摘要 |
The present invention relates to a pharmaceutical composition or a health functional food composition comprising, as an active ingredient, any one selected from a group consisting of a compound expressed by Chemical Formula 1, a pharmaceutically acceptable salt of the compound expressed by Chemical Formula 1, a compound expressed by Chemical Formula 2, and a pharmaceutically acceptable salt of the compound expressed by Chemical Formula 2 for preventing or treating granular cell tumor of ovary. By comprising any one selected from a group consisting of a compound expressed by Chemical Formula 1, a pharmaceutically acceptable salt of the compound expressed by Chemical Formula 1, a compound expressed by Chemical Formula 2, and a pharmaceutically acceptable salt of the compound expressed by Chemical Formula 2 as an active ingredient, the composition of the present invention inhibits Glycogen synthase kinase 3-beta (GSK3beta) to thereby have an effect of inhibiting phosphorylation of serine, which is a 33rd amino acid of forkhead box L2 (FOXL2) protein. Therefore, the composition of the present invention can be useful as a composition for preventing or treating granular cell tumor of ovary. In addition, it is expected that the composition of the present invention can be useful as a health functional food composition. |
