DOSING REGIMEN FOR USE OF CELGOSIVIR AS AN ANTIVIRAL THERAPEUTIC FOR DENGUE VIRUS INFECTION

摘要

Methods of treating a dengue virus (DENV) infection in a human subject, comprising administering to the human subject a compound of Formula (I), or pharmaceutical composition comprising a compound of Formula (I): A compound of Formula (I) can be administered within 48 to 72 hours of fever onset due to dengue infection and then every.6 to 1-2-hours until there is an improvement in the infection. The methods of the invention can be used to treat primary and secondary DENV 1-4 viral infections.