Use of a Polyurethane Foam as a Wound Dressing in Negative Pressure Therapy

摘要

A device for negative pressure wound therapy having a cover material for air-tight sealing of the wound space connected to a negative pressure source; and a wound dressing having an open-cell polyurethane foam. The open-cell polyurethane foam has special properties, in particular a tensile strength after three days of storage in bovine serum, measured in accordance with DIN 53571, between 80 kPa and 300 kPa. The open-cell polyurethane foam may be used as a wound dressing in negative pressure wound therapy.

主权项

1. A device for negative pressure wound therapy comprising
(a) a cover material for air-tight sealing of the wound space; (b) optionally, a connector of a negative pressure source; and (c) an open-cell polyurethane foam as a wound dressing, obtained by reaction of a mixture comprising the components (i) polyisocyanate selected from the group consisting of diphenylmethane diisocyanate (MDI), mixtures of monomeric diphenylmethane diisocyanates and higher-nucleus homologues of diphenylmethane diisocyanate (polymeric MDI), tetramethylene diisocyanate (TMDI), hexamethylene diisocyanate (HDI), toluylene diisocyanate (TDI) and mixtures thereof, (ii) polyol, (iii) blowing agent, and (iv) catalyst, wherein the open-cell polyurethane foam has an air permeability of 1,000 to 8,000 l/(m2sec), measured in accordance with DIN EN ISO 9237.