| 发明名称 |
METHODS FOR TARGETED GENOMIC ANALYSIS |
| 摘要 |
The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles. |
| 申请公布号 |
US2014274731(A1) |
申请公布日期 |
2014.09.18 |
| 申请号 |
US201314102285 |
申请日期 |
2013.12.10 |
| 申请人 |
CLEARFORK BIOSCIENCE, INC. |
发明人 |
RAYMOND Christopher K.;ARMOUR Christopher D.;LIM Lee P. |
| 分类号 |
C12N15/10;C12Q1/68 |
主分类号 |
C12N15/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for generating a tagged genomic library comprising:
(a) treating fragmented genomic DNA with end-repair enzymes to generate fragmented end-repaired genomic DNA; and (b) ligating a random nucleic acid tag sequence, and optionally a sample code sequence and/or a PCR primer sequence to the fragmented end-repaired genomic DNA to generate the tagged genomic library. |
| 地址 |
Kirkland WA US |
