发明名称 |
TARGETED POLYMERIC CONJUGATES AND USES THEREOF |
摘要 |
Polymeric conjugates comprising a polymeric backbone having attached thereto a bone targeting moiety and a therapeutically active agent, wherein the bone targeting moiety is attached to one end of the polymeric backbone via a branching unit such that a molar ratio of the bone targeting moiety to the polymer is at least 2:1, are disclosed. Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of bone related disorders are also disclosed. |
申请公布号 |
US2014271483(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
US201214117043 |
申请日期 |
2012.05.10 |
申请人 |
Satchi-Fainaro Ronit;Pasut Gianfranco |
发明人 |
Satchi-Fainaro Ronit;Pasut Gianfranco |
分类号 |
A61K47/24;G01N33/574;A61K49/00;A61K47/48;G01N33/50 |
主分类号 |
A61K47/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Tel-Aviv IL |