| 摘要 |
<p>The invention provided herein discloses, inter alia, compositions of beads (such as, polymeric beads) of substantially identical size and shape encoded with unique information storing identifiers and methods for use of the same in multiplex chemical and biological assays. Accordingly, provided herein are methods for conducting a multiplex assay comprising the steps of: a) contacting a sample with beads in an assay system, wherein each bead in the system comprises an identifier; wherein the system comprises (i) at least one bead with an identifier that is recognized by an imaging processor as a specific assay, and (ii) a plurality of beads, wherein each bead comprises a capture agent immobilized on the surface of the bead that specifically binds to an analyte; and simultaneously or sequentially, in any order: b) identifying the identifier that is recognized by the imaging processor as the specific assay; and c) detecting the binding of the analyte in the sample by analyzing the binding of the analyte to the capture agent immobilized on the surface of the bead based on the identification of the identifier as the specific assay.</p> |
