发明名称 |
PYRAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS |
摘要 |
Provided herein are compounds of the formula (I):;;as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders. |
申请公布号 |
US2014274950(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
US201313798394 |
申请日期 |
2013.03.13 |
申请人 |
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT |
发明人 |
BEESON Craig C.;LINDSEY Christopher C.;PETERSON Yuri K.;ROHRER Baerbel |
分类号 |
C07D403/06;C07D403/04;C07F7/10 |
主分类号 |
C07D403/06 |
代理机构 |
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代理人 |
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主权项 |
1. The compound according to formula (I): wherein: R1 is lower alkyl, trimethylsilyl or pyridinyl; one of R2 or R2′ is absent and the other is —CH2R3 or —CH2C(O)R3; and R3 is pyridinyl, 1H-indol-3-yl, unsubstituted phenyl or phenyl mono-, bi- or tri-substituted independently with alkoxy, or a pharmaceutically acceptable salt thereof. |
地址 |
Charleston SC US |