| 发明名称 |
ELECTROCHEMICAL METHODS AND DEVICES FOR AMENDING URINE SAMPLES FOR IMMUNOSENSOR DETECTION |
| 摘要 |
The present invention is directed to methods and devices for amending undiluted and partially diluted urine samples in a manner suitable for performing immunoassays for target analytes, for example NGAL. Generally, the urine sample is treated with reagents including at least one of buffer materials, water soluble proteins, urease, and other interferent mitigants. These reagents control the pH of the urine sample in a manner suitable for immuno-binding reactions and ameliorate interferences, particularly during the detection step. |
| 申请公布号 |
US2014273034(A1) |
申请公布日期 |
2014.09.18 |
| 申请号 |
US201414206532 |
申请日期 |
2014.03.12 |
| 申请人 |
Abbott Point of Care Inc. |
发明人 |
Di Tullio Katrina;Collier G. Bruce;Campbell John Lewis Emerson |
| 分类号 |
G01N33/543 |
主分类号 |
G01N33/543 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A device configured to perform an immunoassay for a target analyte in a urine sample, the device comprising:
a first region comprising reagents configured to amend the urine sample, wherein the reagents comprise a water soluble protein and a buffer; and a second region comprising at least one electrode configured to determine a concentration of the target analyte in the amended urine sample, wherein the first region is configured to provide a dissolved concentration of the water soluble protein within the amended urine sample in a range of about 0.02 to 225 mg/mL. |
| 地址 |
Princeton NJ US |
