发明名称 |
BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF PRIMARY SCLEROSING CHOLANGITIS AND INFLAMMATORY BOWEL DISEASE |
摘要 |
<p>Provided herein are methods of treating or ameliorating primary sclerosing cholangitis and inflammatory bowel disease by administering to an individual in need thereof a therapeutically effective amount of an Apical Sodium-dependent Bile Acid Transporter Inhibitor (ASBTI) or a pharmaceutically acceptable salt thereof. Also provided are methods for treating or ameliorating primary sclerosing cholangitis comprising administering to an individual in need thereof a therapeutically effective amount of ASBTI or a pharmaceutically acceptable salt thereof.</p> |
申请公布号 |
CA2907230(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
CA20142907230 |
申请日期 |
2014.03.14 |
申请人 |
LUMENA PHARMACEUTICALS, INC. |
发明人 |
GEDULIN, BRONISLAVA;GREY, MICHAEL;O'DONNELL, NIALL;KELLER, BRADLEY T. |
分类号 |
A61K31/155;A61K31/38;A61K31/554;A61P1/16 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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