| 发明名称 |
CEFTOLOZANE PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
Pharmaceutical formulations can include ceftolozane and an alkalizing agent such as L-arginine. |
| 申请公布号 |
US2014274992(A1) |
申请公布日期 |
2014.09.18 |
| 申请号 |
US201414213997 |
申请日期 |
2014.03.14 |
| 申请人 |
Cubist Pharmaceuticals, Inc. |
发明人 |
Damour Nicole Miller;Walsh Jacqueline Marie;Terracciano Joseph |
| 分类号 |
A61K31/546;A61K47/18;A61K31/431 |
主分类号 |
A61K31/546 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising ceftolozane obtained by a process comprising lyophilizing a solution comprising ceftolozane sulfate, about 450 to 500 mg sodium chloride and L-arginine in an amount effective to provide a pH of 5-7 to the solution, and lyophilizing the solution to obtain pharmaceutical composition comprising stabilized ceftolozane. |
| 地址 |
Lexington MA US |
