| 发明名称 |
Therapeutic and Diagnostic Methods for Manipulating Phagocytosis Through Calreticulin and Low Density Lipoprotein-Related Receptor |
| 摘要 |
Therapeutic and diagnostic methods are provided, which methods relate to the expression of calreticulin on cancer cells and hematopoietic cells. |
| 申请公布号 |
US2014271683(A1) |
申请公布日期 |
2014.09.18 |
| 申请号 |
US201113996390 |
申请日期 |
2011.12.21 |
| 申请人 |
Chao Mark P.;Weissman-Tsukamoto Rachel;Jaiswal Siddhartha;Majeti Ravindra;Weissman Irving L. |
发明人 |
Chao Mark P.;Weissman-Tsukamoto Rachel;Jaiswal Siddhartha;Majeti Ravindra;Weissman Irving L. |
| 分类号 |
A61K39/395;G01N33/68;C12Q1/68;A61K35/28;G01N33/574 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of targeting or depleting cancer cells, the method comprising:
contacting cancer cells with an agent that specifically binds calreticulin in order to target or deplete the cells. |
| 地址 |
Mountain View CA US |
