发明名称 |
SALTS, CO-CRYSTALS, AND POLYMORPHS OF AN ANXIOLYTIC COMPOUND |
摘要 |
The present invention provides amorphous arid crystalline forms of 1-ethyl-6-(indan-2- ylamino)-3-(morpholine-4-carbonyl)-1,8-naphthyridin-4-one (compound 1), and salts, co- crystals, and pharmaceutical compositions thereof. The invention also provides methods of treating and/or preventing a disease, such as a central nervous system disease (e.g., an anxiety disorder), using the amorphous and crystelline forms, and salts, co-crystals, and pharmaceutical compositions thereof. |
申请公布号 |
WO2014138812(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
WO2014AU00272 |
申请日期 |
2014.03.14 |
申请人 |
BIONOMICS LIMITED;IRONWOOD PHARMACEUTICALS, INC. |
发明人 |
FLYNN, BERNARD LUKE;DHARAM, PAUL;HARVEY, ANDREW JOHN;SETHURAMAN, VASU V.;FORSLUND, RAYMOND E.;XUE, SONG;LIVINGSTON, ROB;HASHASH, AHMAD |
分类号 |
C07D417/04;A61K31/4375;A61P25/00;A61P25/04;A61P25/20;A61P25/22;A61P25/24;A61P25/28 |
主分类号 |
C07D417/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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