| 发明名称 |
Methods and compositions for treating hepatitis C virus |
| 摘要 |
C:/NRPortblDCM 46351. DOC-1/10/2012 The present invention provides a method for the treatment of a hepatitis C virus infection in a host, the method comprising administering to the host an effective amount of a purine or pyrimidine p-D-2'-methyl-ribofuranosyl nucleoside or a stabilized phosphate prodrug thereof. </N0 NI 0r OH OH OH OH OH OH p-D-2'-CH 3riboG p-D-2'-CH 3-riboC P-D-2'-CH 3-riboU OH OH OH OH OHOH P-D-2'-CH3riboA 0 Ci-2'-0H34bo D-CHriboT HD N N N :NH Ha H HY OH OH OH OH J - D-1-CH,7bo P-iboA -- 1'-C ftDgriboGb If NHN N O N, HO%.JHO~IH FIAU Ribavirin Chemical Structure of illustrative Nucleosides |
| 申请公布号 |
AU2014203816(A1) |
申请公布日期 |
2014.09.18 |
| 申请号 |
AU20140203816 |
申请日期 |
2014.07.10 |
| 申请人 |
IDENIX PHARMACEUTICALS, INC.;UNIVERSITA DEGLI STUDI DI CAGLIARI |
发明人 |
SOMMADOSSI, JEAN-PIERRE;LACOLLA, PAULO |
| 分类号 |
C07D473/18;A61K31/513;A61K31/52;A61K31/522;A61K31/7068;A61K31/7072;A61K31/7076;A61K31/708;A61P1/16;A61P31/12;A61P31/14;C07D405/04;C07D473/30;C07D473/34;C07H19/04;C07H19/06;C07H19/067;C07H19/073;C07H19/10;C07H19/16;C07H19/167;C07H19/173;C07H19/20 |
主分类号 |
C07D473/18 |
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