发明名称 |
MICRORNA 130A,B AS A TUMOR SUPPRESSOR AND SENSITIZING AGENT FOR CHEMOTHERAPY |
摘要 |
The present invention provides a method of improving a therapeutic response to a cancer treatment, in a subject, the method comprising administering an effective amount of an agent that enhances the expression of microRNA-130 or an agent that mimics the effects of microRNA-130. Further provided is a method of treating a cancer in a subject in need of such treatment comprising the step of administering an effective amount of a microRNA-130 or an agent that enhances the expression of microRNA-130. |
申请公布号 |
EP2691548(A4) |
申请公布日期 |
2014.09.17 |
申请号 |
EP20120765452 |
申请日期 |
2012.04.02 |
申请人 |
UNIVERSITY OF HOUSTON;BAYLOR COLLEGE OF MEDICINE |
发明人 |
GUANARATNE, PREETHI;BENHAM, ASHLEY, L.;ANDERSON, MATTHEW, L. |
分类号 |
C12Q1/68;A61K31/7105;A61K31/713;C12N15/11 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|