发明名称 具有改进的耐水性的化妆防晒制剂或皮肤科防晒制剂
摘要 一种化妆防晒制剂或皮肤科防晒制剂,该制剂除了UV滤光剂之外还包括乳化剂聚甘油-10硬脂酸酯。制剂具有改进的耐水性。
申请公布号 CN104053427A 申请公布日期 2014.09.17
申请号 CN201280027864.1 申请日期 2012.06.05
申请人 拜尔斯道夫股份有限公司 发明人 斯蒂芬尼·冯塔登;曼努埃拉·克勒
分类号 A61K8/39(2006.01)I;A61K8/37(2006.01)I;A61K8/92(2006.01)I;A61K8/06(2006.01)I;A61Q17/04(2006.01)I 主分类号 A61K8/39(2006.01)I
代理机构 中原信达知识产权代理有限责任公司 11219 代理人 李楠;安翔
主权项 一种耐水的化妆防晒制剂或皮肤科防晒制剂,所述防晒制剂包括一种或多种UV滤光物质、相对制剂的总质量小于6重量%的聚甘油‑10硬脂酸酯,其特征在于,所述制剂不含有卵磷脂并且所述制剂将由以下所组成的O/W乳浊液制剂4和5:<tables num="0001" id="ctbl0001"><table><tgroup cols="3"><colspec colname="c001" colwidth="69%" /><colspec colname="c002" colwidth="15%" /><colspec colname="c003" colwidth="16%" /><tbody><row><entry morerows="1"> </entry><entry morerows="1">4</entry><entry morerows="1">5</entry></row><row><entry morerows="1">泛醇</entry><entry morerows="1">0.7</entry><entry morerows="1">0</entry></row><row><entry morerows="1">丁二醇</entry><entry morerows="1">5</entry><entry morerows="1">10</entry></row><row><entry morerows="1">丙二醇</entry><entry morerows="1">5</entry><entry morerows="1"> </entry></row><row><entry morerows="1">苄索氯铵</entry><entry morerows="1">0.5</entry><entry morerows="1">0.9</entry></row><row><entry morerows="1">月桂酰精氨酸乙酯</entry><entry morerows="1">1.0</entry><entry morerows="1">0.5</entry></row><row><entry morerows="1">医用白油</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">棕榈酸异丙酯</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">辛酸/癸酸甘油三酯</entry><entry morerows="1">0</entry><entry morerows="1">1.00</entry></row><row><entry morerows="1">鲸蜡硬脂醇</entry><entry morerows="1">2.5</entry><entry morerows="1">4.00</entry></row><row><entry morerows="1">鲸蜡醇</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">线性硅油</entry><entry morerows="1">0</entry><entry morerows="1">0.50</entry></row><row><entry morerows="1">环状硅油</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">C12‑15醇苯甲酸酯</entry><entry morerows="1">0</entry><entry morerows="1">2.00</entry></row><row><entry morerows="1">牛油树脂</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">二辛基醚</entry><entry morerows="1">10</entry><entry morerows="1">0</entry></row><row><entry morerows="1">碳酸二辛酯</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">甘油硬脂酸酯</entry><entry morerows="1">2.4</entry><entry morerows="1">2.4</entry></row><row><entry morerows="1">木薯淀粉</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">甘油</entry><entry morerows="1">8</entry><entry morerows="1">8</entry></row><row><entry morerows="1">丁二醇</entry><entry morerows="1">1</entry><entry morerows="1">0</entry></row><row><entry morerows="1">柠檬酸</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">45%苛性钠溶液</entry><entry morerows="1">0.25</entry><entry morerows="1">1</entry></row><row><entry morerows="1">聚甘油‑10肉豆蔻酸酯</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">聚甘油‑10硬脂酸酯</entry><entry morerows="1">1</entry><entry morerows="1">1</entry></row><row><entry morerows="1">聚丙烯酸,钠盐(卡波姆981)</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">丙烯酸/VP交联聚合物</entry><entry morerows="1">0.5</entry><entry morerows="1">0.75</entry></row></tbody></tgroup></table></tables><tables num="0002" id="ctbl0002"><table><tgroup cols="3"><colspec colname="c001" colwidth="68%" /><colspec colname="c002" colwidth="15%" /><colspec colname="c003" colwidth="17%" /><tbody><row><entry morerows="1">EDTA三钠</entry><entry morerows="1"> </entry><entry morerows="1">1</entry></row><row><entry morerows="1">甲氧基肉桂酸乙基己酯</entry><entry morerows="1">2</entry><entry morerows="1">0</entry></row><row><entry morerows="1">丁基甲氧基二苯甲酰基甲烷</entry><entry morerows="1">0</entry><entry morerows="1">2</entry></row><row><entry morerows="1">苯基苯并咪唑磺酸,钠盐</entry><entry morerows="1">0</entry><entry morerows="1">2</entry></row><row><entry morerows="1">水杨酸乙基己酯</entry><entry morerows="1">0</entry><entry morerows="1">2</entry></row><row><entry morerows="1">涂覆了硅酮的二氧化钛</entry><entry morerows="1">0.3600</entry><entry morerows="1">0</entry></row><row><entry morerows="1">奥克立林</entry><entry morerows="1">0</entry><entry morerows="1">2</entry></row><row><entry morerows="1">香料</entry><entry morerows="1">0</entry><entry morerows="1">0.20</entry></row><row><entry morerows="1">水</entry><entry morerows="1">加至100</entry><entry morerows="1">加至100</entry></row></tbody></tgroup></table></tables>以及由以下所组成的O/W乳浊液制剂49和50:<tables num="0003" id="ctbl0003"><table><tgroup cols="3"><colspec colname="c001" colwidth="67%" /><colspec colname="c002" colwidth="16%" /><colspec colname="c003" colwidth="17%" /><tbody><row><entry morerows="1"> </entry><entry morerows="1">49</entry><entry morerows="1">50</entry></row><row><entry morerows="1">泛醇</entry><entry morerows="1">0.7</entry><entry morerows="1">0</entry></row><row><entry morerows="1">丁二醇</entry><entry morerows="1">5</entry><entry morerows="1">10</entry></row><row><entry morerows="1">丙二醇</entry><entry morerows="1">5</entry><entry morerows="1"> </entry></row><row><entry morerows="1">甲基异噻唑啉酮</entry><entry morerows="1">0.06</entry><entry morerows="1"> </entry></row><row><entry morerows="1">苄索氯铵</entry><entry morerows="1">0.15</entry><entry morerows="1"> </entry></row><row><entry morerows="1">吡罗克酮乙醇胺盐</entry><entry morerows="1">0.15</entry><entry morerows="1"> </entry></row><row><entry morerows="1">月桂酰精氨酸乙酯</entry><entry morerows="1">0.15</entry><entry morerows="1">1.75</entry></row><row><entry morerows="1">医用白油</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">棕榈酸异丙酯</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">辛酸/癸酸甘油三酯</entry><entry morerows="1">0</entry><entry morerows="1">1.00</entry></row><row><entry morerows="1">鲸蜡硬脂醇</entry><entry morerows="1">2.5</entry><entry morerows="1">4.00</entry></row><row><entry morerows="1">鲸蜡醇</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">线性硅油</entry><entry morerows="1">0</entry><entry morerows="1">0.50</entry></row><row><entry morerows="1">环状硅油</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">C12‑15醇苯甲酸酯</entry><entry morerows="1">0</entry><entry morerows="1">2.00</entry></row><row><entry morerows="1">牛油树脂</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">二辛基醚</entry><entry morerows="1">10</entry><entry morerows="1">0</entry></row><row><entry morerows="1">碳酸二辛酯</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">甘油硬脂酸酯</entry><entry morerows="1">2.4</entry><entry morerows="1">2.4</entry></row><row><entry morerows="1">木薯淀粉</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">甘油</entry><entry morerows="1">8</entry><entry morerows="1">8</entry></row><row><entry morerows="1">柠檬酸</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">45%苛性钠溶液</entry><entry morerows="1">0.25</entry><entry morerows="1">1</entry></row><row><entry morerows="1">聚甘油‑10肉豆蔻酸酯</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row></tbody></tgroup></table></tables><tables num="0004" id="ctbl0004"><table><tgroup cols="3"><colspec colname="c001" colwidth="66%" /><colspec colname="c002" colwidth="17%" /><colspec colname="c003" colwidth="17%" /><tbody><row><entry morerows="1">聚甘油‑10硬脂酸酯</entry><entry morerows="1">1</entry><entry morerows="1">1</entry></row><row><entry morerows="1">聚丙烯酸,钠盐</entry><entry morerows="1">0</entry><entry morerows="1">0</entry></row><row><entry morerows="1">丙烯酸/VP交联聚合物</entry><entry morerows="1">0.5</entry><entry morerows="1">0.75</entry></row><row><entry morerows="1">EDTA三钠</entry><entry morerows="1"> </entry><entry morerows="1">1</entry></row><row><entry morerows="1">甲氧基肉桂酸乙基己酯</entry><entry morerows="1">2</entry><entry morerows="1">0</entry></row><row><entry morerows="1">丁基甲氧基二苯甲酰基甲烷</entry><entry morerows="1">0</entry><entry morerows="1">2</entry></row><row><entry morerows="1">苯基苯并咪唑磺酸</entry><entry morerows="1">0</entry><entry morerows="1">2</entry></row><row><entry morerows="1">水杨酸乙基己酯</entry><entry morerows="1">0</entry><entry morerows="1">2</entry></row><row><entry morerows="1">二氧化钛+三甲氧基辛基硅烷</entry><entry morerows="1">0.3600</entry><entry morerows="1">0</entry></row><row><entry morerows="1">奥克立林</entry><entry morerows="1">0</entry><entry morerows="1">2</entry></row><row><entry morerows="1">香料</entry><entry morerows="1">0</entry><entry morerows="1">0.20</entry></row><row><entry morerows="1">水</entry><entry morerows="1">加至100</entry><entry morerows="1">加至100</entry></row></tbody></tgroup></table></tables>排除在外,其中,数值为相对于所述制剂总质量的重量份额。
地址 德国汉堡