| 发明名称 |
SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS |
| 摘要 |
The present invention relates to the synthesis and application of novel chiral/achiral substituted methyl formyl reagents to modify pharmaceutical agents and/or biologically active substances to modify the physicochemical, biological and/or pharmacokinetic properties of the resulting compounds from the unmodified original agent. |
| 申请公布号 |
EP2693876(A4) |
申请公布日期 |
2014.09.17 |
| 申请号 |
EP20120768375 |
申请日期 |
2012.04.09 |
| 申请人 |
SPHAERA PHARMA PTE. LTD |
发明人 |
DUGAR, SUNDEEP;MAHAJAN, DINESH;HOLLINGER, FRANK, PETER |
| 分类号 |
A61K31/11;C07D213/80;C07D213/803;C07D213/81;C07D213/82;C07D295/20;C07D305/14;C07D401/04;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D471/04;C07D487/04;C07D487/22;C07D491/147;C07D491/22;C07D495/14 |
主分类号 |
A61K31/11 |
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