摘要 |
<p>A method of predicting clinical outcome for a human subject diagnosed with colorectal cancer following surgical resection of said cancer is disclosed. A normalized expression level is determined of an RNA transcript of MYBL2, or an expression product thereof, in a biological sample comprising cancer cells obtained from said human subject. The likelihood of a positive clinical outcome for said human subject is then predicted based on said normalized expression level, wherein normalized expression of an RNA transcript of MYBL2, or an expression product thereof, is positively correlated with an increased likelihood of a positive clinical outcome.</p> |
申请人 |
GENOMIC HEALTH, INC.;NSABP FOUNDATION, INC. |
发明人 |
COWENS, WAYNE;BAKER, JOFFRE;HACKETT, JAMES;WATSON, DREW;PAIK, SOONMYUNG;CLARK, KIM |