发明名称 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
摘要 The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect soluble tumor necrosis factor receptor superfamily member 6, optionally together with one or more markers selected from the group consisting of soluble p-selectin, protein NOV homolog, soluble epidermal growth factor receptor, netrin-4, haptoglobin, heat shock protein bet-1, alpha-1-antitrypsin, leukocyte elastase, soluble tumor necrosis factor ligand superfamily member 6, soluble intercellular adhesion molecule 2, active caspase-3, and soluble platelet endothelial cell adhesion molecule as diagnostic and prognostic biomarkers in renal injuries.
申请公布号 EP2743702(A3) 申请公布日期 2014.09.17
申请号 EP20140151433 申请日期 2009.08.28
申请人 ASTUTE MEDICAL, INC. 发明人 ANDERBERG, JOSEPH;GRAY, JEFF;MCPHERSON, PAUL;NAKAMURA, KEVIN
分类号 G01N33/68 主分类号 G01N33/68
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