发明名称 Composition for oral cavity
摘要 The present invention relates to an oral care composition, which contains a compound represented by the formula (A):; (wherein, R represents a substituted or unsubstituted, linear or branched alkyl group having from 6 to 18 carbon atoms, G represents a galactose residue, m stands for an integer of from 0 to 200, and n stands for an integer of from 1 to 30); and a coaggregation inhibitor of bacteria of the genus Fusobacterium and cariogenic bacteria, which contains the compound as an effective ingredient. The composition for oral cavity according to the present invention inhibits coaggregation of bacteria of the genus Fusobacterium with cariogenic bacteria so that it has an excellent caries preventive effect.
申请公布号 US8834852(B2) 申请公布日期 2014.09.16
申请号 US201012772492 申请日期 2010.05.03
申请人 Kao Corporation 发明人 Itano Morihide;Kayane Shigeto;Ueno Katsuya;Mizushima Hiromoto
分类号 A61K8/00;A61K8/18;A61Q11/00;A01N43/04;A61K31/70;A61Q17/00;A61K8/60;A61K8/34;A61K8/39;A61K8/73;A61K31/7028;A61K31/7032 主分类号 A61K8/00
代理机构 Sterne, Kessler, Goldstein & Fox P.L.L.C. 代理人 Sterne, Kessler, Goldstein & Fox P.L.L.C.
主权项 1. A method for inhibiting coaggregation between bacteria of the genus Fusobacterium and cariogenic bacteria in the oral cavity, said method comprising (a) applying, into said oral cavity, a paste or liquid composition that comprises an effective amount of a compound represented by the following formula (A):wherein, R represents a substituted or unsubstituted, linear or branched alkyl group having from 8 to 14 carbon atoms, G represents a galactose residue, E represents a hydrogen atom or a methyl group, m stands for an integer of from 0 to 200, and n stands for an integer of from 1 to 30, and (b) inhibiting said coaggregation of said bacteria of the genus Fusobacterium with said cariogenic bacteria in said oral cavity and decreasing the ratio of the cariogenic bacteria count to the total streptococci count in plaque in said oral cavity as a result of said applying.
地址 Tokyo JP