Photodynamic therapy for tumors with localized delivery

摘要

Methods and systems for treatment of hypoxic tumors are provided, including the steps of positioning a delivery device in a bodily cavity adjacent to tumor tissue, delivering an oxygenating agent to the tumor tissue via the delivery device and radiating the tumor tissue with radiation. Methods and systems of treatment of tumors are also provided, including the steps of positioning a delivery device in a bodily cavity adjacent to tumor tissue, delivering a photosensitizing agent to the tumor tissue via the delivery device, and radiating the tumor tissue with light.

主权项

1. A method of treatment of tumors comprising the steps of:
positioning a catheter having at least one inflatable balloon positioned adjacent a distal end thereof in a bodily cavity adjacent to target tissue; delivering a photosensitizing agent to the target tissue via at least one opening in said catheter; radiating the target tissue with light; and repeatedly inflating and at least partially deflating said at least one inflatable balloon by supplying fluid thereto and withdrawing fluid therefrom via said catheter such that a resecting outer surface of said balloon contacts the radiated target tissue and resects said tissue.