| 发明名称 |
Therapeutic application of cembranoids against HIV virus replication, HIV-associated neurocognitive disorders and HIV virus-induced inflammation |
| 摘要 |
A method and composition for suppressing replication of the HIV-1 virus strains, modulating the production and liberation of inflammatory mediators; and the prevention and treatment of neurocognitive disorders. The method comprises administering to a subject an effective amount of an a macrocyclic diterpenoid, such as 4R cembranoid. |
| 申请公布号 |
US8835512(B2) |
申请公布日期 |
2014.09.16 |
| 申请号 |
US201213649828 |
申请日期 |
2012.10.11 |
| 申请人 |
|
发明人 |
Ferchmin Peter Andrew;Eterovic Vesna Ana;Rodriguez Jose Wigberto;Rios-Olivares Eddy Oscar;Baccin Martins Antonio Henrique |
| 分类号 |
A61K31/045;A61K45/06;A61K31/047 |
主分类号 |
A61K31/045 |
| 代理机构 |
Harbin & Hein PLLC |
代理人 |
Harbin Lawrence;Harbin & Hein PLLC |
| 主权项 |
1. A method for treatment of an HIV-infected subject, comprising:
administering to a subject an effective amount of a 4R cembranoid. |
| 地址 |
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