Neural Stimulation for treatment of metabolic syndrome and type 2 diabetes

摘要

Systems and methods are described for treating metabolic syndrome and/or Type 2 diabetes, and/or one or more of their attendant conditions, by neural stimulation. In one embodiment, an implantable pulse generator is electrically coupled to a peripheral nerve, such as the splanchnic nerve. Neural stimulation configured to either block transmission or stimulate transmission of the peripheral nerve may be used to treat metabolic syndrome and Type 2 diabetes.

主权项

1. A method of lowering blood pressure in a subject comprising:
establishing a baseline blood pressure; electrically stimulating the splanchnic nerve with at least one stimulation pattern for a first time period; subsequent to the step of stimulating the splanchnic nerve, waiting a second time period for the mean arterial blood pressure of the subject to drop to or below the established baseline blood pressure; repeating the steps of stimulating and waiting until the blood pressure of the subject is lower that the baseline blood pressure.