Glucose management and dialysis method and apparatus

摘要

A process and apparatus are provided for managing and adjusting glucose levels in the blood of a patient during dialysis. The apparatus is a dialysis apparatus to treat patients with renal disease which includes a glucose scavenger to remove excess glucose from the blood before returning the blood to the patient and/or a device to increase blood glucose levels in the blood when the glucose level is below a threshold level. The glucose scavenger can include a glucose binding protein, boronic acid derivative, boronic ester derivative or mixture thereof bonded to the surface of a support such as a fiber bundle in a cartridge or the inner surface of tubing used in the apparatus.

主权项

1. A process for treating a patient, the process comprising:
removing blood from the patient and passing the blood through a treatment device to treat the blood, where said treatment device is a dialyser to treat the blood by removing wastes from the blood; measuring the glucose level of the blood; directing the blood to a glucose scavenging unit when the measured glucose level is measured above a threshold level and removing glucose from the blood, and producing a reduced glucose level blood, or directing the blood to a glucose increasing unit when the measured glucose is below a threshold level and increasing the blood glucose level, where said glucose scavenging unit is positioned in a line between the dialyser and the patient; and returning the resulting treated blood to said patient.