| 发明名称 | Vault compositions for immunization | ||
| 摘要 | Methods and compositions are provided herein for immunizing a subject by administering to the subject an effective amount of an immunogenic peptide or an immunogenic fragment or variant thereof incorporated within a vault-like particle carrier. The methods and compositions advantageously exhibit enhanced ability to induce cell-mediated immunity and/or antibody-based immunity. | ||
| 申请公布号 | US8834896(B2) | 申请公布日期 | 2014.09.16 |
| 申请号 | US201313737963 | 申请日期 | 2013.01.10 |
| 申请人 | The Regents of the University of California | 发明人 | Kickhoefer Valerie A.;Rome Leonard H.;Kelly Kathleen A.;Champion Cheryl I. |
| 分类号 | A61K39/02 | 主分类号 | A61K39/02 |
| 代理机构 | Canady + Lortz LLP | 代理人 | Sundby, Esq. Suzannah K.;Canady + Lortz LLP |
| 主权项 | 1. A method for stimulating a cellular immune response in a subject in need thereof, comprising administering to the subject an effective amount of a vaccine comprising a pathogen immunogenic peptide or a pathogen immunogenic fragment or variant thereof incorporated within a vault-like particle, wherein the vault-like particle comprises MVP, thereby stimulating a cellular immune response. | ||
| 地址 | Oakland CA US | ||